Ardox-X® is a stabilized active oxygen donating complex that provides a controlled release of non-radical, anionic oxygen species to treat oral infections and other oral issues. Unlike traditional oxygen donors like hydrogen peroxide, it releases active oxygen without creating damaging free radicals, making it safe for long-term use without harming DNA or mucosal cells. The mechanism of active oxygen involves several stages of interaction with the oral environment and pathogenic bacteria:
Our Ardox-X® complex is disrupted upon contact with the mucosa, saliva, or specific enzymes, triggering a gradual release of active oxygen.
Because it does not generate free radicals, it is not cytotoxic and does not cause cell death in mucosal cells, osteoblasts (bone-building cells), or blood cells.
Ardox-X® works by oxidizing proteins within the dental biofilm, which increases the penetrability of the biofilm. This allows the oxygen to reach bacteria deep within gingival pockets that large molecules (like antibiotics or chlorhexidine) often cannot reach.
Ardox-X® is used as an adjunctive treatment. The oxygen-enriched microenvironment has a proven positive effect on the infected gingival pockets. Studies showed an average of 56% reduction in pocket depth after three months of treatment.
This is an inflammatory condition around dental implants. Ardox-X® is used as an adjunctive treatment as the active oxygen helps reduce biofilm formation on implant surfaces without damaging the tissues.
Our technology is used in toothpastes and mouthwashes for daily oral care to prevent and treat gum inflammation.
Oral Malodour: Active oxygen is highly effective at neutralizing volatile sulfur compounds (VSCs) in the oral cavity for up to six hours, outperforming some standard chlorhexidine rinses.
It effectively bleaches tooth discolorations through oxidative transformation without the sensitivity or DNA damage associated with high-concentration peroxide treatments.
It can be used to inhibit Mutans streptococci, which are responsible for initial caries or “white spots” often seen during orthodontic treatment.
